| 1 | 3 | Radio Systems Corp.
10427 PetSafe Way
Knoxville, TN 37932
| 865-777-5404
radiosystemscorporation.com
494/1,300
| Pet products: PetSafe, Invisible Fence Brand, SportDOG, Premier Pet, Kurgo
| Rob Candelino
CEO
1991
|
| 2 | 1 | Siemens Healthineers
810 Innovation Drive
Knoxville, TN 37932
| 865-218-2000
medical.siemens.com
457/NA
| Positron emission tomography (PET) portion of PET/computed tomography (CT) imaging systems; headquarters for Siemens’ PETNET Solutions network of PET radiopharmacies
| James Williams
Barry Scott
Head, molecular imaging
CEO, PETNET Solutions
2005
|
| 3 | 2 | DeRoyal Industries
200 DeBusk Lane
Powell, TN 37849
| 865-938-7828
deroyal.com
400/1,735
| Electrosurgical and surgical equipment, temperature monitoring and waste fluid management systems, RFID inventory control system, negative pressure wound therapy
| Pete DeBusk
Chairman
1973
|
| 4 | 4 | Bandit Lites
2233 Sycamore Drive
Knoxville, TN 37921
| 865-971-3071
banditlites.com
300/NA
| Entertainment and architectural illumination rental, sales, design and installation
| Michael Strickland
Chairman
1968
|
| 5 | 5 | Protomet
2400 Maremont Parkway
Loudon, TN 37774
| 865-425-0600
protomet.com
250/250
| Products developed specifically for the marine industry include wakeboard towers, racks, flip seats, grab rails, dash components, optics-grade mirrors, and wiring harnesses
| Jeff Bohanan
President
1997
|
| 6 | 7 | Aqua-Chem
3001 E. John Sevier Highway
Knoxville, TN 37914
| 865-544-2065
aqua-chem.com
165/NA
| Water purification technologies for pharmaceutical, beverage, energy, land-based desalination, commercial marine, government
| Shane DeWitt
CEO
2005
|
| 7 | 9 | PerfectServe
2160 Lakeside Centre Way, Ste. 310
Knoxville, TN 37922
| 877-844-7726
perfectserve.com
150/320
| Clinical communication and provider scheduling technology used by more than 500 healthcare organizations across the country
| NA
NA
1999
|
| 8 | 6 | AESSEAL Inc.
355 Dunavant Road
Rockford, TN 37853
| 865-531-0192
aesseal.com
150/200
| Design, manufacture of mechanical seals and seal support systems used for environmental containment of chemical process fluid or rotating equipment
| Peter Rouleau
CEO
1992
|
| 9 | 11 | Provision Healthcare
1400 Dowell Springs Blvd., Ste. 350
Knoxville, TN 37909
| 865-770-7000
provisionhealthcare.com
146/178
| Healthcare services, cancer screening, diagnosis and treatment, proton therapy treatment centers, advanced proton therapy systems, clinical research
| Terry Douglass
Chairman, CEO
2012
|
| 10 | 8 | Electric Power Research Institute (EPRI)
942 Corridor Park Blvd.
Knoxville, TN 37932
| 865-218-8000
epri.com
131/1,210
| Technology solutions that enable the transformation of power systems to be more flexible, resilient and connected
| Daniel Brooks
VP, integrated grid
2005
|
| 11 | 10 | Centrus Technical Solutions
400 Centrifuge Way
Oak Ridge, TN 37830
| 865-241-7007
centrusenergy.com/cts
106/272
| Provides technical solutions for the engineering, development, prototyping and manufacturing of complex engineered products
| Larry Cutlip
Senior VP, field operations
2002
|
| 12 | 14 | Vacuum Technology Incorporated (VTI)
1003 Alvin Weinberg Drive
Oak Ridge, TN 37830
| 865-481-3342
vacuumtechnology.com
80/80
| Calibrated leaks and vacuum leak testing systems
| George Solomon
Michelle Solomon
Mark Boeckmann
President, co-founder
Chief accounting, financial officer
Chief scientist, co-founder
1986
|
| 13 | 12 | Analysis and Measurement Services Corp. (AMS)
AMS 9119 Cross Park Drive
Knoxville, TN 37923
| 865-691-1756
ams-corp.com
70/90
| Qualifying the instrumentation and control systems of nuclear power plants through laboratory and in-plant testing services and specialized testing equipment and advanced monitoring technologies
| Dr. H.M. Hashemian
Brent D. Shumaker
President, CEO
Senior engineering manager
1977
|
| 14 | 15 | Cryomagnetics
1006 Alvin Weinberg Drive
Oak Ridge, TN 37830
| 865-482-9551
cryomagnetics.com
65/NA
| Design, development and manufacture of superconducting magnets, cryogenic systems, control electronics
| Michael Coffey
President
1983
|
| 15 | 12 | Uster Technologies
456 Troy Circle
Knoxville, TN 37919
| 865-588-9716
uster.com
60/NA
| Design, manufacture, install precision measuring instruments used for quality measurement and certification for the textile industry
| Peyman Dekhordi
COO
1948
|
| 16 | 16 | Technology for Energy Corp.
10737 Lexington Drive
Knoxville, TN 37932
| 865-966-5856
tec-usa.com
55/72
| Aircraft and helicopter on-the-wing ground support equipment, equipment for electric power metering, power quality, revenue protection of the electric power industry, monitoring equipment for nuclear power plants, X-ray diffraction analyzers
| William Simpkins
President, CEO
1975
|
| 17 | 17 | MS Technology
137 Union Valley Road
Oak Ridge, TN 37830
| 865-483-0895
mstechnology.com
53/NA
| Nuclear process support equipment including control panels and specialty furnaces and heaters
| Doyle Inklebarger
President, CEO
1994
|
| 18 | 19 | Cubic Transportation Systems, ITS/GRIDSMART
10545 Hardin Valley Road
Knoxville, TN 37932
| 865-466-3860
gridsmart.com
38/63
| Traffic management system deploying proprietary technology and software that gathers important traffic data to adjust signal timing and traffic flow strategies, enables real-time remote monitoring and visual assessment
| Jeff Price
VP, GM, Cubic ITS
2007
|
| 19 | 18 | Proton Power, Inc.
487 Sam Rayburn Parkway
Lenoir City, TN 37771
| 865-376-9002
protonpower.com
34/35
| Manufactures a patented renewable energy system that utilizes renewable biomass and waste sources to generate electricity, heat, synthetic fuels, hydrogen, biochar and graphene
| Sam Weaver
President
2005
|
| 20 | 20 | Acato Information Management, LLC
173 Mitchell Road
Oak Ridge, TN 37830
| 865-381-1120
acatoim.com
26/29
| Software quality assurance (SQA)
| Catherine Toth
President, CEO
2010
|
