1 | 3 | Radio Systems Corp. 10427 PetSafe Way Knoxville, TN 37932
| 865-777-5404 radiosystemscorporation.com 494/1,300
| Pet products: PetSafe, Invisible Fence Brand, SportDOG, Premier Pet, Kurgo
| Rob Candelino CEO 1991
|
2 | 1 | Siemens Healthineers 810 Innovation Drive Knoxville, TN 37932
| 865-218-2000 medical.siemens.com 457/NA
| Positron emission tomography (PET) portion of PET/computed tomography (CT) imaging systems; headquarters for Siemens’ PETNET Solutions network of PET radiopharmacies
| James Williams Barry Scott Head, molecular imaging CEO, PETNET Solutions 2005
|
3 | 2 | DeRoyal Industries 200 DeBusk Lane Powell, TN 37849
| 865-938-7828 deroyal.com 400/1,735
| Electrosurgical and surgical equipment, temperature monitoring and waste fluid management systems, RFID inventory control system, negative pressure wound therapy
| Pete DeBusk Chairman 1973
|
4 | 4 | Bandit Lites 2233 Sycamore Drive Knoxville, TN 37921
| 865-971-3071 banditlites.com 300/NA
| Entertainment and architectural illumination rental, sales, design and installation
| Michael Strickland Chairman 1968
|
5 | 5 | Protomet 2400 Maremont Parkway Loudon, TN 37774
| 865-425-0600 protomet.com 250/250
| Products developed specifically for the marine industry include wakeboard towers, racks, flip seats, grab rails, dash components, optics-grade mirrors, and wiring harnesses
| Jeff Bohanan President 1997
|
6 | 7 | Aqua-Chem 3001 E. John Sevier Highway Knoxville, TN 37914
| 865-544-2065 aqua-chem.com 165/NA
| Water purification technologies for pharmaceutical, beverage, energy, land-based desalination, commercial marine, government
| Shane DeWitt CEO 2005
|
7 | 9 | PerfectServe 2160 Lakeside Centre Way, Ste. 310 Knoxville, TN 37922
| 877-844-7726 perfectserve.com 150/320
| Clinical communication and provider scheduling technology used by more than 500 healthcare organizations across the country
| NA NA 1999
|
8 | 6 | AESSEAL Inc. 355 Dunavant Road Rockford, TN 37853
| 865-531-0192 aesseal.com 150/200
| Design, manufacture of mechanical seals and seal support systems used for environmental containment of chemical process fluid or rotating equipment
| Peter Rouleau CEO 1992
|
9 | 11 | Provision Healthcare 1400 Dowell Springs Blvd., Ste. 350 Knoxville, TN 37909
| 865-770-7000 provisionhealthcare.com 146/178
| Healthcare services, cancer screening, diagnosis and treatment, proton therapy treatment centers, advanced proton therapy systems, clinical research
| Terry Douglass Chairman, CEO 2012
|
10 | 8 | Electric Power Research Institute (EPRI) 942 Corridor Park Blvd. Knoxville, TN 37932
| 865-218-8000 epri.com 131/1,210
| Technology solutions that enable the transformation of power systems to be more flexible, resilient and connected
| Daniel Brooks VP, integrated grid 2005
|
11 | 10 | Centrus Technical Solutions 400 Centrifuge Way Oak Ridge, TN 37830
| 865-241-7007 centrusenergy.com/cts 106/272
| Provides technical solutions for the engineering, development, prototyping and manufacturing of complex engineered products
| Larry Cutlip Senior VP, field operations 2002
|
12 | 14 | Vacuum Technology Incorporated (VTI) 1003 Alvin Weinberg Drive Oak Ridge, TN 37830
| 865-481-3342 vacuumtechnology.com 80/80
| Calibrated leaks and vacuum leak testing systems
| George Solomon Michelle Solomon Mark Boeckmann President, co-founder Chief accounting, financial officer Chief scientist, co-founder 1986
|
13 | 12 | Analysis and Measurement Services Corp. (AMS) AMS 9119 Cross Park Drive Knoxville, TN 37923
| 865-691-1756 ams-corp.com 70/90
| Qualifying the instrumentation and control systems of nuclear power plants through laboratory and in-plant testing services and specialized testing equipment and advanced monitoring technologies
| Dr. H.M. Hashemian Brent D. Shumaker President, CEO Senior engineering manager 1977
|
14 | 15 | Cryomagnetics 1006 Alvin Weinberg Drive Oak Ridge, TN 37830
| 865-482-9551 cryomagnetics.com 65/NA
| Design, development and manufacture of superconducting magnets, cryogenic systems, control electronics
| Michael Coffey President 1983
|
15 | 12 | Uster Technologies 456 Troy Circle Knoxville, TN 37919
| 865-588-9716 uster.com 60/NA
| Design, manufacture, install precision measuring instruments used for quality measurement and certification for the textile industry
| Peyman Dekhordi COO 1948
|
16 | 16 | Technology for Energy Corp. 10737 Lexington Drive Knoxville, TN 37932
| 865-966-5856 tec-usa.com 55/72
| Aircraft and helicopter on-the-wing ground support equipment, equipment for electric power metering, power quality, revenue protection of the electric power industry, monitoring equipment for nuclear power plants, X-ray diffraction analyzers
| William Simpkins President, CEO 1975
|
17 | 17 | MS Technology 137 Union Valley Road Oak Ridge, TN 37830
| 865-483-0895 mstechnology.com 53/NA
| Nuclear process support equipment including control panels and specialty furnaces and heaters
| Doyle Inklebarger President, CEO 1994
|
18 | 19 | Cubic Transportation Systems, ITS/GRIDSMART 10545 Hardin Valley Road Knoxville, TN 37932
| 865-466-3860 gridsmart.com 38/63
| Traffic management system deploying proprietary technology and software that gathers important traffic data to adjust signal timing and traffic flow strategies, enables real-time remote monitoring and visual assessment
| Jeff Price VP, GM, Cubic ITS 2007
|
19 | 18 | Proton Power, Inc. 487 Sam Rayburn Parkway Lenoir City, TN 37771
| 865-376-9002 protonpower.com 34/35
| Manufactures a patented renewable energy system that utilizes renewable biomass and waste sources to generate electricity, heat, synthetic fuels, hydrogen, biochar and graphene
| Sam Weaver President 2005
|
20 | 20 | Acato Information Management, LLC 173 Mitchell Road Oak Ridge, TN 37830
| 865-381-1120 acatoim.com 26/29
| Software quality assurance (SQA)
| Catherine Toth President, CEO 2010
|